Antiplasmodial Activity of [(Aryl)arylsulfanylmethyl]Pyridine

A series of [(aryl)arylsufanylmethyl]pyridines (AASMP) have been synthesized. These compounds inhibited hemozoin formation, formed complexes (K(D) = 12 to 20 μM) with free heme (ferriprotoporphyrin IX) at a pH close to the pH of the parasite food vacuole, and exhibited antimalarial activity in vitro...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Kumar, Sanjay, Das, Sajal Kumar, Dey, Sumanta, Maity, Pallab, Guha, Mithu, Choubey, Vinay, Panda, Gautam, Bandyopadhyay, Uday
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Mechanisms of Action: Physiological Effects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224759/
https://ncbi.nlm.nih.gov/pubmed/18025110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00898-07
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars