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Binding of Human Papillomavirus Type 16 E6 to E6AP Is Not Required for Activation of hTERT

The human papillomavirus (HPV) type 16 (HPV16) E6 protein stimulates transcription of the catalytic subunit of telomerase, hTERT, in epithelial cells. It has been reported that binding to the ubiquitin ligase E6AP is required for this E6 activity, with E6 directing E6AP to the hTERT promoter. We pre...

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Bibliographic Details
Main Authors: Sekaric, Pedja, Cherry, Jonathan J., Androphy, Elliot J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224393/
https://ncbi.nlm.nih.gov/pubmed/17942561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01776-07
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