Human Papillomavirus Type 16 E6 Promotes Retinoblastoma Protein Phosphorylation and Cell Cycle Progression

We show that E6 proteins from benign human papillomavirus type 1 (HPV1) and oncogenic HPV16 have the ability to alter the regulation of the G(1)/S transition of the cell cycle in primary human fibroblasts. Overexpression of both viral proteins induces cellular proliferation, retinoblastoma (pRb) pho...

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Autores principales: Malanchi, Ilaria, Accardi, Rosita, Diehl, Frank, Smet, Anouk, Androphy, Elliot, Hoheisel, Jörg, Tommasino, Massimo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Transformation and Oncogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC533917/
https://ncbi.nlm.nih.gov/pubmed/15564485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13769-13778.2004
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