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Induction of pRb Degradation by the Human Papillomavirus Type 16 E7 Protein Is Essential To Efficiently Overcome p16(INK4a)-Imposed G(1) Cell Cycle Arrest

It has previously been shown that the E7 protein from the cutaneous human papillomavirus type 1 (HPV1), which is associated with benign skin lesions, binds the product of the tumor suppressor gene retinoblastoma (pRb) with an efficiency similar to that of the E7 protein from the oncogenic HPV type 1...

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Detalhes bibliográficos
Main Authors: Giarrè, Marianna, Caldeira, Sandra, Malanchi, Ilaria, Ciccolini, Francesca, Leão, Maria João, Tommasino, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114225/
https://ncbi.nlm.nih.gov/pubmed/11312342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.10.4705-4712.2001
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