Induction of pRb Degradation by the Human Papillomavirus Type 16 E7 Protein Is Essential To Efficiently Overcome p16(INK4a)-Imposed G(1) Cell Cycle Arrest

It has previously been shown that the E7 protein from the cutaneous human papillomavirus type 1 (HPV1), which is associated with benign skin lesions, binds the product of the tumor suppressor gene retinoblastoma (pRb) with an efficiency similar to that of the E7 protein from the oncogenic HPV type 1...

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Hlavní autoři: Giarrè, Marianna, Caldeira, Sandra, Malanchi, Ilaria, Ciccolini, Francesca, Leão, Maria João, Tommasino, Massimo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC114225/
https://ncbi.nlm.nih.gov/pubmed/11312342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.10.4705-4712.2001
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