Human papillomavirus infection and immunohistochemical expression of cell cycle proteins pRb, p53, and p16(INK4a) in sinonasal diseases

BACKGROUND: We aimed to clarify the possible role of human papillomavirus (HPV) infection in the malignant transformation of sinonasal inverted papilloma (IP). METHODS: Subjects comprised 32 patients with chronic rhinosinusitis (CRS), 17 with IP, 5 with IP and squamous cell carcinoma (IP + SCC), and...

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Published in:Infect Agent Cancer
Main Authors: Yamashita, Yukashi, Hasegawa, Masahiro, Deng, Zeyi, Maeda, Hiroyuki, Kondo, Shunsuke, Kyuna, Asanori, Matayoshi, Sen, Agena, Shinya, Uehara, Takayuki, Kouzaki, Hideaki, Shimizu, Takeshi, Ikegami, Taro, Ganaha, Akira, Suzuki, Mikio
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524447/
https://ncbi.nlm.nih.gov/pubmed/26244053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13027-015-0019-8
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