Immunization with a Lentivector That Targets Tumor Antigen Expression to Dendritic Cells Induces Potent CD8(+) and CD4(+) T-Cell Responses

Lentivectors stimulate potent immune responses to antigen transgenes and are being developed as novel genetic vaccines. To improve safety while retaining efficacy, we constructed a lentivector in which transgene expression was restricted to antigen-presenting cells using the mouse dectin-2 gene prom...

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Bibliografiske detaljer
Main Authors: Lopes, Luciene, Dewannieux, Marie, Gileadi, Uzi, Bailey, Ranbir, Ikeda, Yasuhiro, Whittaker, Christopher, Collin, Matthew P., Cerundolo, Vincenzo, Tomihari, Mizuki, Ariizumi, Kiyoshi, Collins, Mary K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224357/
https://ncbi.nlm.nih.gov/pubmed/17959670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01289-07
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