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Immunization with a Lentivector That Targets Tumor Antigen Expression to Dendritic Cells Induces Potent CD8(+) and CD4(+) T-Cell Responses
Lentivectors stimulate potent immune responses to antigen transgenes and are being developed as novel genetic vaccines. To improve safety while retaining efficacy, we constructed a lentivector in which transgene expression was restricted to antigen-presenting cells using the mouse dectin-2 gene prom...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2224357/ https://ncbi.nlm.nih.gov/pubmed/17959670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01289-07 |
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