A Non-Tumor Suppressor Role for Basal p19(ARF) in Maintaining Nucleolar Structure and Function

The nucleolus is the center of ribosome synthesis, with the nucleophosmin (NPM) and p19(ARF) proteins antagonizing one another to either promote or inhibit growth. However, basal NPM and ARF proteins form nucleolar complexes whose functions remain unknown. Nucleoli from Arf(−/)(−) cells displayed in...

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Autors principals: Apicelli, Anthony J., Maggi, Leonard B., Hirbe, Angela C., Miceli, Alexander P., Olanich, Mary E., Schulte-Winkeler, Crystal L., Saporita, Anthony J., Kuchenreuther, Michael, Sanchez, José, Weilbaecher, Katherine, Weber, Jason D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223401/
https://ncbi.nlm.nih.gov/pubmed/18070929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00484-07
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