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A Non-Tumor Suppressor Role for Basal p19(ARF) in Maintaining Nucleolar Structure and Function

The nucleolus is the center of ribosome synthesis, with the nucleophosmin (NPM) and p19(ARF) proteins antagonizing one another to either promote or inhibit growth. However, basal NPM and ARF proteins form nucleolar complexes whose functions remain unknown. Nucleoli from Arf(−/)(−) cells displayed in...

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Detalhes bibliográficos
Main Authors: Apicelli, Anthony J., Maggi, Leonard B., Hirbe, Angela C., Miceli, Alexander P., Olanich, Mary E., Schulte-Winkeler, Crystal L., Saporita, Anthony J., Kuchenreuther, Michael, Sanchez, José, Weilbaecher, Katherine, Weber, Jason D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223401/
https://ncbi.nlm.nih.gov/pubmed/18070929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00484-07
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