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Differential Chromatin Looping Regulates CD4 Expression in Immature Thymocytes
Runx1 binds the silencer and represses CD4 transcription in immature thymocytes. In this study, using looping chromatin immunoprecipitation and chromatin conformation capture assays, we demonstrated that interactions between Runx1 and positive elongation factor b (P-TEFb) appose the silencer and enh...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2223376/ https://ncbi.nlm.nih.gov/pubmed/18039856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00909-07 |
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