Distinct, specific IL-17 and IL-22-producing CD4(+) T cell subsets contribute to the human anti-mycobacterial immune response

We investigated whether the pro-inflammatory T cell cytokines interleukin-17 (IL-17) and IL-22 are induced by human mycobacterial infection. Remarkably, >20% of specific cytokine-producing CD4(+) T cells in peripheral blood of healthy, mycobacteria-exposed adults expressed IL-17 or IL-22. Specifi...

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Main Authors: Scriba, Thomas J., Kalsdorf, Barbara, Abrahams, Deborah-Ann, Isaacs, Fatima, Hofmeister, Jessica, Black, Gillian, Hassan, Hisham Y, Wilkinson, Robert J., Walzl, Gerhard, Gelderbloem, Sebastian J., Mahomed, Hassan, Hussey, Gregory D., Hanekom, Willem A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219462/
https://ncbi.nlm.nih.gov/pubmed/18209095
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