Higher human CD4 T cell response to novel Mycobacterium tuberculosis latency associated antigens Rv2660 and Rv2659 in latent infection compared with tuberculosis disease

One third of the world’s population is infected with Mycobacterium tuberculosis (M.tb). A vaccine that would prevent progression to TB disease will have a dramatic impact on the global TB burden. We propose that antigens of M.tb that are preferentially expressed during latent infection will be excel...

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Main Authors: Govender, Lerisa, Abel, Brian, Hughes, E. Jane, Scriba, Thomas J., Kagina, Benjamin M. N., de Kock, Marwou, Walzl, Gerhard, Black, Gillian, Rosenkrands, Ida, Hussey, Gregory D, Mahomed, Hassan, Andersen, Peter, Hanekom, Willem A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376751/
https://ncbi.nlm.nih.gov/pubmed/20974305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.10.022
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