A Small RNA Encoded in the Rv2660c Locus of Mycobacterium tuberculosis Is Induced during Starvation and Infection

Enhanced transcription of the Rv2660c locus in response to starvation of Mycobacterium tuberculosis H37Rv encouraged addition of the predicted Rv2660c protein to an improved vaccine formulation. Using strand-specific RNA sequencing, we show that the up-regulated transcript is in fact a small RNA enc...

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Autors principals: Houghton, Joanna, Cortes, Teresa, Schubert, Olga, Rose, Graham, Rodgers, Angela, De Ste Croix, Megan, Aebersold, Rudolf, Young, Douglas B., Arnvig, Kristine B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861185/
https://ncbi.nlm.nih.gov/pubmed/24348997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080047
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