The rv1184c Locus Encodes Chp2, an Acyltransferase in Mycobacterium tuberculosis Polyacyltrehalose Lipid Biosynthesis

Trehalose glycolipids are found in many bacteria in the suborder Corynebacterineae, but methyl-branched acyltrehaloses are exclusive to virulent species such as the human pathogen Mycobacterium tuberculosis. In M. tuberculosis, the acyltransferase PapA3 catalyzes the formation of diacyltrehalose (DA...

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Udgivet i:J Bacteriol
Main Authors: Touchette, Megan H., Holsclaw, Cynthia M., Previti, Mary L., Solomon, Viven C., Leary, Julie A., Bertozzi, Carolyn R., Seeliger, Jessica C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288680/
https://ncbi.nlm.nih.gov/pubmed/25331437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02015-14
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