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Biosynthesis and Regulation of Sulfomenaquinone, a Metabolite Associated with Virulence in Mycobacterium tuberculosis

Sulfomenaquinone (SMK) is a recently identified metabolite that is unique to the Mycobacterium tuberculosis (M. tuberculosis) complex and is shown to modulate its virulence. Here, we report the identification of the SMK biosynthetic operon that, in addition to a previously identified sulfotransferas...

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Dettagli Bibliografici
Pubblicato in:ACS Infect Dis
Autori principali: Sogi, Kimberly M., Holsclaw, Cynthia M., Fragiadakis, Gabriela K., Nomura, Daniel K., Leary, Julie A., Bertozzi, Carolyn R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505729/
https://ncbi.nlm.nih.gov/pubmed/27933784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00106
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