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Biosynthesis and Regulation of Sulfomenaquinone, a Metabolite Associated with Virulence in Mycobacterium tuberculosis

Sulfomenaquinone (SMK) is a recently identified metabolite that is unique to the Mycobacterium tuberculosis (M. tuberculosis) complex and is shown to modulate its virulence. Here, we report the identification of the SMK biosynthetic operon that, in addition to a previously identified sulfotransferas...

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Vydáno v:ACS Infect Dis
Hlavní autoři: Sogi, Kimberly M., Holsclaw, Cynthia M., Fragiadakis, Gabriela K., Nomura, Daniel K., Leary, Julie A., Bertozzi, Carolyn R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505729/
https://ncbi.nlm.nih.gov/pubmed/27933784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00106
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