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Biosynthesis and Regulation of Sulfomenaquinone, a Metabolite Associated with Virulence in Mycobacterium tuberculosis

Sulfomenaquinone (SMK) is a recently identified metabolite that is unique to the Mycobacterium tuberculosis (M. tuberculosis) complex and is shown to modulate its virulence. Here, we report the identification of the SMK biosynthetic operon that, in addition to a previously identified sulfotransferas...

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Foilsithe in:ACS Infect Dis
Main Authors: Sogi, Kimberly M., Holsclaw, Cynthia M., Fragiadakis, Gabriela K., Nomura, Daniel K., Leary, Julie A., Bertozzi, Carolyn R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505729/
https://ncbi.nlm.nih.gov/pubmed/27933784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00106
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