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Regulation of K(ir) Channels by Intracellular pH and Extracellular K(+) : Mechanisms of Coupling

ROMK channels are regulated by internal pH (pH(i)) and extracellular K(+) (K(+) (o)). The mechanisms underlying this regulation were studied in these channels after expression in Xenopus oocytes. Replacement of the COOH-terminal portion of ROMK2 (Kir1.1b) with the corresponding region of the pH-inse...

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Autors principals: Dahlmann, Anke, Li, Min, Gao, ZhongHua, McGarrigle, Deirdre, Sackin, Henry, Palmer, Lawrence G.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217465/
https://ncbi.nlm.nih.gov/pubmed/15051808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200308989
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