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Ion selectivity and current saturation in inward-rectifier K(+) channels

We investigated the features of the inward-rectifier K channel Kir1.1 (ROMK) that underlie the saturation of currents through these channels as a function of permeant ion concentration. We compared values of maximal currents and apparent K(m) for three permeant ions: K(+), Rb(+), and NH(4)(+). Compa...

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Detalhes bibliográficos
Main Authors: Yang, Lei, Edvinsson, Johan, Sackin, Henry, Palmer, Lawrence G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269791/
https://ncbi.nlm.nih.gov/pubmed/22291146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110727
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