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Interactions of external K(+) and internal blockers in a weak inward-rectifier K(+) channel

We investigated the effects of changing extracellular K(+) concentrations on block of the weak inward-rectifier K(+) channel Kir1.1b (ROMK2) by the three intracellular cations Mg(2+), Na(+), and TEA(+). Single-channel currents were monitored in inside-out patches made from Xenopus laevis oocytes exp...

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Bibliografiske detaljer
Main Authors: Yang, Lei, Edvinsson, Johan, Palmer, Lawrence G.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483120/
https://ncbi.nlm.nih.gov/pubmed/23109715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210835
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