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Antidepressive effect of an inward rectifier K(+) channel blocker peptide, tertiapin-RQ

Renal outer medullary K(+) channel, ROMK (Kir1.1, kcnj1) is expressed in the kidney and brain, but its role in the central nervous system remains unknown. Recent studies suggested an involvement of the ROMK channel in mental diseases. Tertiapin (TPN) is a European honey bee venom peptide and is repo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Okada, Masayoshi, Kozaki, Ikkou, Honda, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665585/
https://ncbi.nlm.nih.gov/pubmed/33186384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233815
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