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Novel Gating Mechanism of Polyamine Block in the Strong Inward Rectifier K Channel Kir2.1

Inward rectifying K channels are essential for maintaining resting membrane potential and regulating excitability in many cell types. Previous studies have attributed the rectification properties of strong inward rectifiers such as Kir2.1 to voltage-dependent binding of intracellular polyamines or M...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Jong-Kook, John, Scott A., Weiss, James N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217169/
https://ncbi.nlm.nih.gov/pubmed/10102936
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