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Epac-Selective cAMP Analogs: New Tools With Which To Evaluate The Signal Transduction Properties Of cAMP-Regulated Guanine Nucleotide Exchange Factors

The identification of 2′-O-methyl substituted adenosine-3′,5′-cyclic monophosphate (cAMP) analogs that activate the Epac family of cAMP-regulated guanine nucleotide exchange factors (cAMP-GEFs, also known as Epac1 and Epac2), has ushered in a new era of cyclic nucleotide research in which previously...

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Detalles Bibliográficos
Main Authors: Holz, George G., Chepurny, Oleg G., Schwede, Frank
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2215344/
https://ncbi.nlm.nih.gov/pubmed/17716863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2007.07.009
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