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”Generation and Maintenance of Listeria-specific CD8+ T cell Responses in Perforin-Deficient Mice Chronically Infected with LCMV”
Disruption of the perforin gene results in primary immunodeficiency and an increased susceptibility to opportunistic pathogens. Perforin-deficient (PKO) mice fail to clear primary lymphocytic choriomeningitis virus (LCMV) Armstrong, resulting in persistent infection and functional exhaustion of viru...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2214839/ https://ncbi.nlm.nih.gov/pubmed/17936870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.08.038 |
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