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CD70-deficiency impairs effector CD8 T cell generation and viral clearance but is dispensable for the recall response to LCMV
CD27 interactions with its ligand, CD70, are thought to be necessary for optimal primary and memory adaptive immune responses to a variety of pathogens. Thus far all studies addressing the function of the CD27-CD70 axis have been performed either in mice lacking CD27, overexpressing CD70, or in whic...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552005/ https://ncbi.nlm.nih.gov/pubmed/23269247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202353 |
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