”Generation and Maintenance of Listeria-specific CD8+ T cell Responses in Perforin-Deficient Mice Chronically Infected with LCMV”

Disruption of the perforin gene results in primary immunodeficiency and an increased susceptibility to opportunistic pathogens. Perforin-deficient (PKO) mice fail to clear primary lymphocytic choriomeningitis virus (LCMV) Armstrong, resulting in persistent infection and functional exhaustion of viru...

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Hlavní autoři: Humphreys, Troy D., Khanolkar, Aaruni, Badovinac, Vladimir P., Harty, John T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214839/
https://ncbi.nlm.nih.gov/pubmed/17936870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.08.038
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