Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway

CD4(+) helper T (Th) cells play a crucial role in the delicate balance between host defense and autoimmune disease. Two important populations of helper T cells are the proinflammatory, interleukin-17 (IL-17)–producing (Th17) cells and the anti-inflammatory forkhead box P3–positive (FoxP3(+)) T regul...

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Détails bibliographiques
Auteurs principaux: Elias, Kevin M., Laurence, Arian, Davidson, Todd S., Stephens, Geoffrey, Kanno, Yuka, Shevach, Ethan M., O'Shea, John J.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2008
Sujets:
Chemokines, Cytokines, and Interleukins
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214761/
https://ncbi.nlm.nih.gov/pubmed/17951529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-06-096438
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