Nonredundant roles for Stat5a/b in directly regulating Foxp3

Stats (signal transducers and activators of transcription) regulate multiple aspects of T-cell fate. T regulatory (Treg) cells are a critical subset that limits immune responses, but the relative importance of Stat5a/b versus Stat3 for Treg cell development has been contentious. We observed that per...

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Detalhes bibliográficos
Main Authors: Yao, Zhengju, Kanno, Yuka, Kerenyi, Marc, Stephens, Geoffrey, Durant, Lydia, Watford, Wendy T., Laurence, Arian, Robinson, Gertraud W., Shevach, Ethan M., Moriggl, Richard, Hennighausen, Lothar, Wu, Changyou, O'Shea, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885496/
https://ncbi.nlm.nih.gov/pubmed/17227828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-11-055756
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