Subset- and tissue-defined STAT5 thresholds control homeostasis and function of innate lymphoid cells

Innate lymphoid cells (ILCs) patrol environmental interfaces to defend against infection and protect barrier integrity. Using a genetic tuning model, we demonstrate that the signal-dependent transcription factor (TF) STAT5 is critical for accumulation of all known ILC subsets in mice and reveal a hi...

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Bibliografische gegevens
Gepubliceerd in:J Exp Med
Hoofdauteurs: Villarino, Alejandro V., Sciumè, Giuseppe, Davis, Fred P., Iwata, Shigeru, Zitti, Beatrice, Robinson, Gertraud W., Hennighausen, Lothar, Kanno, Yuka, O’Shea, John J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2017
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626390/
https://ncbi.nlm.nih.gov/pubmed/28916644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150907
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