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Antigen activation and impaired Fas-induced death-inducing signaling complex formation in T-large-granular lymphocyte leukemia

Clonal T-cell expansion in patients with T-large-granular lymphocyte (LGL) leukemia occurs by an undefined mechanism that may be related to Fas apoptosis resistance. Here, we demonstrate polarized expansion of CD8(+) terminal-memory differentiation in such patients, as demonstrated by CD45RA express...

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書誌詳細
主要な著者: Yang, Jun, Epling-Burnette, P. K., Painter, Jeffrey S., Zou, JianXiang, Bai, Fanqi, Wei, Sheng, Loughran, Thomas P.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214759/
https://ncbi.nlm.nih.gov/pubmed/17993614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-06-093823
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