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Agonist-dependent Single Channel Current and Gating in α(4)β(2)δ and α(1)β(2)γ(2S) GABA(A) Receptors

The family of γ-aminobutyric acid type A receptors (GABA(A)Rs) mediates two types of inhibition in the mammalian brain. Phasic inhibition is mediated by synaptic GABA(A)Rs that are mainly comprised of α(1), β(2), and γ(2) subunits, whereas tonic inhibition is mediated by extrasynaptic GABA(A)Rs comp...

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Detalhes bibliográficos
Main Authors: Keramidas, Angelo, Harrison, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213567/
https://ncbi.nlm.nih.gov/pubmed/18227274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709871
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