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Modulation of Spontaneous and GABA-Evoked Tonic α4β3δ and α4β3γ2L GABA(A) Receptor Currents by Protein Kinase A

Protein kinase A (PKA) has been reported to regulate synaptic αβγ γ-aminobutyric acid type A (GABA(A)) receptor currents, but whether PKA regulates GABA(A) receptor peri- and extrasynaptic tonic currents is unknown. GABA(A) receptors containing α4 subunits are important in mediating tonic inhibition...

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Main Authors: Tang, Xin, Hernandez, Ciria C., Macdonald, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822691/
https://ncbi.nlm.nih.gov/pubmed/19939957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00801.2009
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