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Class Switching in B Cells Lacking 3′ Immunoglobulin Heavy Chain Enhancers

The 40-kb region downstream of the most 3′ immunoglobulin (Ig) heavy chain constant region gene (Cα) contains a series of transcriptional enhancers speculated to play a role in Ig heavy chain class switch recombination (CSR). To elucidate the function of this putative CSR regulatory region, we gener...

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Detalhes bibliográficos
Main Authors: Manis, John P., van der Stoep, Nienke, Tian, Ming, Ferrini, Roger, Davidson, Laurie, Bottaro, Andrea, Alt, Frederick W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213411/
https://ncbi.nlm.nih.gov/pubmed/9782119
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