Replacement of germ-line epsilon promoter by gene targeting alters control of immunoglobulin heavy chain class switching.
Recent work has shown that the ability of cytokines to direct immunoglobulin heavy chain class-switch recombination to particular heavy chain constant (C) region (CH) genes correlates with the induction of specific germ-line CH transcripts. To test the role of germ-line transcripts in class switchin...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46370/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8475119/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.8.3705 |
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