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Differential Regulation and ATP Requirement for Caspase-8 and Caspase-3 Activation during CD95- and Anticancer Drug–induced Apoptosis

Apoptosis is induced by different stimuli, among them triggering of the death receptor CD95, staurosporine, and chemotherapeutic drugs. In all cases, apoptosis is mediated by caspases, although it is unclear how these diverse apoptotic stimuli cause protease activation. Two regulatory pathways have...

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Bibliografske podrobnosti
Main Authors: Ferrari, Davide, Stepczynska, Ania, Los, Marek, Wesselborg, Sebastian, Schulze-Osthoff, Klaus
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213396/
https://ncbi.nlm.nih.gov/pubmed/9730899
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