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Activation and Caspase-mediated Inhibition of PARP: A Molecular Switch between Fibroblast Necrosis and Apoptosis in Death Receptor Signaling

Death ligands not only induce apoptosis but can also trigger necrosis with distinct biochemical and morphological features. We recently showed that in L929 cells CD95 ligation induces apoptosis, whereas TNF elicits necrosis. Treatment with anti-CD95 resulted in typical apoptosis characterized by cas...

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Detalhes bibliográficos
Main Authors: Los, Marek, Mozoluk, Malgorzata, Ferrari, Davide, Stepczynska, Anna, Stroh, Christopher, Renz, Andrea, Herceg, Zdenko, Wang, Zhao-Qi, Schulze-Osthoff, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC99613/
https://ncbi.nlm.nih.gov/pubmed/11907276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-05-0272
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