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Activation and Caspase-mediated Inhibition of PARP: A Molecular Switch between Fibroblast Necrosis and Apoptosis in Death Receptor Signaling

Death ligands not only induce apoptosis but can also trigger necrosis with distinct biochemical and morphological features. We recently showed that in L929 cells CD95 ligation induces apoptosis, whereas TNF elicits necrosis. Treatment with anti-CD95 resulted in typical apoptosis characterized by cas...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Los, Marek, Mozoluk, Malgorzata, Ferrari, Davide, Stepczynska, Anna, Stroh, Christopher, Renz, Andrea, Herceg, Zdenko, Wang, Zhao-Qi, Schulze-Osthoff, Klaus
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Cell Biology 2002
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC99613/
https://ncbi.nlm.nih.gov/pubmed/11907276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-05-0272
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