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Ribavirin and Alpha Interferon Enhance Death Receptor-Mediated Apoptosis and Caspase Activation in Human Hepatoma Cells

The molecular mechanisms underlying the clinical effects of alpha interferon (IFN) and ribavirin are not understood. Elimination of infected cells occurs in part by cytotoxic T lymphocytes (CTLs) expressing CD95 ligand and thereby attacking target cells which are positive for the death receptor CD95...

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Detalhes bibliográficos
Main Authors: Schlosser, Stephan F., Schuler, Markus, Berg, Christoph P., Lauber, Kirsten, Schulze-Osthoff, Klaus, Schmahl, Friedrich Wilhelm, Wesselborg, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155820/
https://ncbi.nlm.nih.gov/pubmed/12760867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.6.1912-1921.2003
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