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Bruton's Tyrosine Kinase Is Essential for Human B Cell Tolerance
Most polyreactive and antinuclear antibodies are removed from the human antibody repertoire during B cell development. To elucidate how B cell receptor (BCR) signaling may regulate human B cell tolerance, we tested the specificity of recombinant antibodies from single peripheral B cells isolated fro...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2213290/ https://ncbi.nlm.nih.gov/pubmed/15466623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040920 |
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