CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance

Hyper-IgM (HIGM) syndromes are primary immunodeficiencies characterized by defects of class switch recombination and somatic hypermutation. HIGM patients who carry mutations in the CD40-ligand (CD40L) gene expressed by CD4(+) T cells suffer from recurrent infections and often develop autoimmune diso...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Hervé, Maxime, Isnardi, Isabelle, Ng, Yen-shing, Bussel, James B., Ochs, Hans D., Cunningham-Rundles, Charlotte, Meffre, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2007
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118633/
https://ncbi.nlm.nih.gov/pubmed/17562816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062287
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky