CD4(+)CD25(+) regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner

Tumor growth promotes the expansion of CD4(+)CD25(+) regulatory T (T reg) cells that counteract T cell–mediated immune responses. An inverse correlation between natural killer (NK) cell activation and T reg cell expansion in tumor-bearing patients, shown here, prompted us to address the role of T re...

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Main Authors: Ghiringhelli, François, Ménard, Cédric, Terme, Magali, Flament, Caroline, Taieb, Julien, Chaput, Nathalie, Puig, Pierre E., Novault, Sophie, Escudier, Bernard, Vivier, Eric, Lecesne, Axel, Robert, Caroline, Blay, Jean-Yves, Bernard, Jacky, Caillat-Zucman, Sophie, Freitas, Antonio, Tursz, Thomas, Wagner-Ballon, Orianne, Capron, Claude, Vainchencker, William, Martin, François, Zitvogel, Laurence
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213209/
https://ncbi.nlm.nih.gov/pubmed/16230475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051511
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