Dendritic Cell-Derived Exosomes Promote Natural Killer Cell Activation and Proliferation: A Role for NKG2D Ligands and IL-15Rα

Dendritic cell (DC) derived-exosomes (Dex) are nanomeric vesicles harboring functional MHC/peptide complexes promoting T cell-dependent tumor rejection. In the first Phase I trial using peptide-pulsed Dex, the observation of clinical regressions in the absence of T cell responses prompted the search...

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Detalhes bibliográficos
Main Authors: Viaud, Sophie, Terme, Magali, Flament, Caroline, Taieb, Julien, André, Fabrice, Novault, Sophie, Escudier, Bernard, Robert, Caroline, Caillat-Zucman, Sophie, Tursz, Thomas, Zitvogel, Laurence, Chaput, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657211/
https://ncbi.nlm.nih.gov/pubmed/19319200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004942
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