Natural killer cells in non-hematopoietic malignancies

by Desbois, Mélanie, Rusakiewicz, Sylvie, Locher, Clara, Zitvogel, Laurence, Chaput, Nathalie
Published 2012

Estimating causal effects of time-dependent exposures on a binary endpoint in a high-dimensional setting

by Asvatourian, Vahé, Coutzac, Clélia, Chaput, Nathalie, Robert, Caroline, Michiels, Stefan, Lanoy, Emilie
Published in BMC Med Res Methodol (2018)

Oxazaphosphorines combined with immune checkpoint blockers: dose-dependent tuning between immune and cytotoxic effects

by Delahousse, Julia, Skarbek, Charles, Desbois, Mélanie, Perfettini, Jean-Luc, Chaput, Nathalie, Paci, Angelo
Published in J Immunother Cancer (2020)

Treatment of gastric peritoneal carcinomatosis by combining complete surgical resection of lesions and intraperitoneal immunotherapy using catumaxomab

by Goéré, Diane, Gras-Chaput, Nathalie, Aupérin, Anne, Flament, Caroline, Mariette, Christophe, Glehen, Olivier, Zitvogel, Laurence, Elias, Dominique
Published 2014

IL-15 superagonist RLI has potent immunostimulatory properties on NK cells: implications for antimetastatic treatment

by Desbois, Mélanie, Béal, Coralie, Charrier, Mélinda, Besse, Benjamin, Meurice, Guillaume, Cagnard, Nicolas, Jacques, Yannick, Béchard, David, Cassard, Lydie, Chaput, Nathalie
Published in J Immunother Cancer (2020)

Dendritic Cell Maturation Overrules H-2d–Mediated Natural Killer T (Nkt) Cell Inhibition: Critical Role for B7 in Cd1d-Dependent Nkt Cell Interferon γ Production

by Ikarashi, Yoshinori, Mikami, Rumiko, Bendelac, Albert, Terme, Magali, Chaput, Nathalie, Terada, Masahiro, Tursz, Thomas, Angevin, Eric, Lemonnier, François A., Wakasugi, Hiro, Zitvogel, Laurence
Published 2001

Current and future biomarkers for outcomes with immunotherapy in non-small cell lung cancer

by Duchemann, Boris, Remon, Jordi, Naigeon, Marie, Cassard, Lydie, Jouniaux, Jean Mehdi, Boselli, Lisa, Grivel, Jonathan, Auclin, Edouard, Desnoyer, Aude, Besse, Benjamin, Chaput, Nathalie
Published in Transl Lung Cancer Res (2021)

Dendritic Cell-Derived Exosomes Promote Natural Killer Cell Activation and Proliferation: A Role for NKG2D Ligands and IL-15Rα

by Viaud, Sophie, Terme, Magali, Flament, Caroline, Taieb, Julien, André, Fabrice, Novault, Sophie, Escudier, Bernard, Robert, Caroline, Caillat-Zucman, Sophie, Tursz, Thomas, Zitvogel, Laurence, Chaput, Nathalie
Published 2009

Integrating Circulating Biomarkers in the Immune Checkpoint Inhibitor Treatment in Lung Cancer

by Duchemann, Boris, Remon, Jordi, Naigeon, Marie, Mezquita, Laura, Ferrara, Roberto, Cassard, Lydie, Jouniaux, Jean Mehdi, Boselli, Lisa, Grivel, Jonathan, Auclin, Edouard, Desnoyer, Aude, Besse, Benjamin, Chaput, Nathalie
Published in Cancers (Basel) (2020)

Phase I clinical trial combining imatinib mesylate and IL-2 in refractory cancer patients: IL-2 interferes with the pharmacokinetics of imatinib mesylate

by Pautier, Patricia, Locher, Clara, Robert, Caroline, Deroussent, Alain, Flament, Caroline, Le Cesne, Axel, Rey, Annie, Bahleda, Ratislav, Ribrag, Vincent, Soria, Jean-Charles, Vassal, Gilles, Eggermont, Alexander, Zitvogel, Laurence, Chaput, Nathalie, Paci, Angelo
Published 2013

Phase I clinical trial combining imatinib mesylate and IL-2: HLA-DR(+) NK cell levels correlate with disease outcome

by Chaput, Nathalie, Flament, Caroline, Locher, Clara, Desbois, Mélanie, Rey, Annie, Rusakiewicz, Sylvie, Poirier-Colame, Vichnou, Pautier, Patricia, Le Cesne, Axel, Soria, Jean-Charles, Paci, Angelo, Rosenzwajg, Michelle, Klatzmann, David, Eggermont, Alexander, Robert, Caroline, Zitvogel, Laurence
Published 2013

Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

by Casares, Noelia, Pequignot, Marie O., Tesniere, Antoine, Ghiringhelli, François, Roux, Stéphan, Chaput, Nathalie, Schmitt, Elise, Hamai, Ahmed, Hervas-Stubbs, Sandra, Obeid, Michel, Coutant, Frédéric, Métivier, Didier, Pichard, Evelyne, Aucouturier, Pierre, Pierron, Gérard, Garrido, Carmen, Zitvogel, Laurence, Kroemer, Guido
Published 2005

Human preprocalcitonin self-antigen generates TAP-dependent and -independent epitopes triggering optimised T-cell responses toward immune-escaped tumours

by Durgeau, Aurélie, Virk, Yasemin, Gros, Gwendoline, Voilin, Elodie, Corgnac, Stéphanie, Djenidi, Fayçal, Salmon, Jérôme, Adam, Julien, de Montpréville, Vincent, Validire, Pierre, Ferrone, Soldano, Chouaib, Salem, Eggermont, Alexander, Soria, Jean-Charles, Lemonnier, François, Tartour, Eric, Chaput, Nathalie, Besse, Benjamin, Mami-Chouaib, Fathia
Published in Nat Commun (2018)

Impact of Intercurrent Introduction of Steroids on Clinical Outcomes in Advanced Non-Small-Cell Lung Cancer (NSCLC) Patients under Immune-Checkpoint Inhibitors (ICI)

by De Giglio, Andrea, Mezquita, Laura, Auclin, Edouard, Blanc-Durand, Félix, Riudavets, Mariona, Caramella, Caroline, Martinez, Gala, Benitez, Jose Carlos, Martín-Romano, Patricia, El-Amarti, Lamiae, Hendriks, Lizza, Ferrara, Roberto, Naltet, Charles, Lavaud, Pernelle, Gazzah, Anas, Adam, Julien, Planchard, David, Chaput, Nathalie, Besse, Benjamin
Published in Cancers (Basel) (2020)

CD4(+)CD25(+) regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner

by Ghiringhelli, François, Ménard, Cédric, Terme, Magali, Flament, Caroline, Taieb, Julien, Chaput, Nathalie, Puig, Pierre E., Novault, Sophie, Escudier, Bernard, Vivier, Eric, Lecesne, Axel, Robert, Caroline, Blay, Jean-Yves, Bernard, Jacky, Caillat-Zucman, Sophie, Freitas, Antonio, Tursz, Thomas, Wagner-Ballon, Orianne, Capron, Claude, Vainchencker, William, Martin, François, Zitvogel, Laurence
Published 2005

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

by Ma, Yuting, Aymeric, Laetitia, Locher, Clara, Mattarollo, Stephen R., Delahaye, Nicolas F., Pereira, Pablo, Boucontet, Laurent, Apetoh, Lionel, Ghiringhelli, François, Casares, Noëlia, Lasarte, Juan José, Matsuzaki, Goro, Ikuta, Koichi, Ryffel, Bernard, Benlagha, Kamel, Tesnière, Antoine, Ibrahim, Nicolas, Déchanet-Merville, Julie, Chaput, Nathalie, Smyth, Mark J., Kroemer, Guido, Zitvogel, Laurence
Published 2011

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

by Ma, Yuting, Aymeric, Laetitia, Locher, Clara, Mattarollo, Stephen R., Delahaye, Nicolas F., Pereira, Pablo, Boucontet, Laurent, Apetoh, Lionel, Ghiringhelli, François, Casares, Noëlia, Lasarte, Juan José, Matsuzaki, Goro, Ikuta, Koichi, Ryffel, Bernard, Benlagha, Kamel, Tesnière, Antoine, Ibrahim, Nicolas, Déchanet-Merville, Julie, Chaput, Nathalie, Smyth, Mark J., Kroemer, Guido, Zitvogel, Laurence
Published 2011

Association of the Lung Immune Prognostic Index With Immune Checkpoint Inhibitor Outcomes in Patients With Advanced Non–Small Cell Lung Cancer

by Mezquita, Laura, Auclin, Edouard, Ferrara, Roberto, Charrier, Melinda, Remon, Jordi, Planchard, David, Ponce, Santiago, Ares, Luis Paz, Leroy, Laura, Audigier-Valette, Clarisse, Felip, Enriqueta, Zerón-Medina, Jorge, Garrido, Pilar, Brosseau, Solenn, Zalcman, Gérard, Mazieres, Julien, Caramela, Caroline, Lahmar, Jihene, Adam, Julien, Chaput, Nathalie, Soria, Jean Charles, Besse, Benjamin
Published in JAMA Oncol (2018)

Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

by Escudier, Bernard, Dorval, Thierry, Chaput, Nathalie, André, Fabrice, Caby, Marie-Pierre, Novault, Sophie, Flament, Caroline, Leboulaire, Christophe, Borg, Christophe, Amigorena, Sebastian, Boccaccio, Catherine, Bonnerot, Christian, Dhellin, Olivier, Movassagh, Mojgan, Piperno, Sophie, Robert, Caroline, Serra, Vincent, Valente, Nancy, Le Pecq, Jean-Bernard, Spatz, Alain, Lantz, Olivier, Tursz, Thomas, Angevin, Eric, Zitvogel, Laurence
Published 2005

Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer

by Coutzac, Clélia, Jouniaux, Jean-Mehdi, Paci, Angelo, Schmidt, Julien, Mallardo, Domenico, Seck, Atmane, Asvatourian, Vahe, Cassard, Lydie, Saulnier, Patrick, Lacroix, Ludovic, Woerther, Paul-Louis, Vozy, Aurore, Naigeon, Marie, Nebot-Bral, Laetitia, Desbois, Mélanie, Simeone, Ester, Mateus, Christine, Boselli, Lisa, Grivel, Jonathan, Soularue, Emilie, Lepage, Patricia, Carbonnel, Franck, Ascierto, Paolo Antonio, Robert, Caroline, Chaput, Nathalie
Published in Nat Commun (2020)