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DAP12 (KARAP) amplifies inflammation and increases mortality from endotoxemia and septic peritonitis
DAP12 (KARAP) is a transmembrane signaling adaptor for a family of innate immunoreceptors that have been shown to activate granulocytes and monocytes/macrophages, amplifying production of inflammatory cytokines. Contrasting with these data, recent studies suggest that DAP12 signaling has an inhibito...
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| Asıl Yazarlar: | , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Rockefeller University Press
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2213081/ https://ncbi.nlm.nih.gov/pubmed/16061725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050986 |
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