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PKCβ regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1
The B cell antigen receptor (BCR)–mediated activation of IκB kinase (IKK) and nuclear factor–κB require protein kinase C (PKC)β; however, the mechanism by which PKCβ regulates IKK is unclear. Here, we demonstrate that another protein kinase, TGFβ-activated kinase (TAK)1, is essential for IKK activat...
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| Главные авторы: | , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212994/ https://ncbi.nlm.nih.gov/pubmed/16301747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051591 |
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