Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-κB activation

The bacterial pathogens of the genus Yersinia, the causative agents of plague, septicemia, and gastrointestinal syndromes, use a type III secretion system to inject virulence factors into host target cells. One virulence factor, YopJ, is essential for the death of infected macrophages and can block...

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Bibliographic Details
Main Authors: Zhou, Honglin, Monack, Denise M., Kayagaki, Nobuhiko, Wertz, Ingrid, Yin, Jianpin, Wolf, Beni, Dixit, Vishva M.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2005
Subjects:
Brief Definitive Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212976/
https://ncbi.nlm.nih.gov/pubmed/16301742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051194
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