Cytosolic phospholipase A(2)α–deficient mice are resistant to experimental autoimmune encephalomyelitis

Experimental autoimmune encephalomyelitis (EAE), a Th1-mediated inflammatory disease of the central nervous system (CNS), is a model of human multiple sclerosis. Cytosolic phospholipase A(2) α (cPLA(2) α), which initiates production of prostaglandins, leukotrienes, and platelet-activating factor, is...

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Detalhes bibliográficos
Main Authors: Marusic, Suzana, Leach, Michael W., Pelker, Jeffrey W., Azoitei, Mihai L., Uozumi, Naonori, Cui, Junqing, Shen, Marina W.H., DeClercq, Charlene M., Miyashiro, Joy S., Carito, Brenda A., Thakker, Paresh, Simmons, David L., Leonard, John P., Shimizu, Takao, Clark, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212947/
https://ncbi.nlm.nih.gov/pubmed/16172261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050665
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