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Cytosolic phospholipase A2α mediates Pseudomonas aeruginosa LPS-induced airway constriction of CFTR -/- mice

BACKGROUND: Lungs of cystic fibrosis (CF) patients are chronically infected with Pseudomonas aeruginosa. Increased airway constriction has been reported in CF patients but underplaying mechanisms have not been elucidated. Aim: to examine the effect of P. aeruginosa LPS on airway constriction in CF m...

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Detalhes bibliográficos
Main Authors: Wu, Yong-Zheng, Abolhassani, Mohammad, Ollero, Mario, Dif, Fariel, Uozumi, Naonori, Lagranderie, Micheline, Shimizu, Takao, Chignard, Michel, Touqui, Lhousseine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873258/
https://ncbi.nlm.nih.gov/pubmed/20429932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-49
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