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Pseudomonas aeruginosa LPS or Flagellin Are Sufficient to Activate TLR-Dependent Signaling in Murine Alveolar Macrophages and Airway Epithelial Cells

BACKGROUND: The human lung is exposed to a large number of airborne pathogens as a result of the daily inhalation of 10,000 liters of air. Innate immunity is thus essential to defend the lungs against these pathogens. This defense is mediated in part through the recognition of specific microbial lig...

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Detalhes bibliográficos
Main Authors: Raoust, Eloïse, Balloy, Viviane, Garcia-Verdugo, Ignacio, Touqui, Lhousseine, Ramphal, Reuben, Chignard, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752798/
https://ncbi.nlm.nih.gov/pubmed/19806220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007259
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