Cytosolic phospholipase A(2)α–deficient mice are resistant to experimental autoimmune encephalomyelitis

Experimental autoimmune encephalomyelitis (EAE), a Th1-mediated inflammatory disease of the central nervous system (CNS), is a model of human multiple sclerosis. Cytosolic phospholipase A(2) α (cPLA(2) α), which initiates production of prostaglandins, leukotrienes, and platelet-activating factor, is...

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Autors principals: Marusic, Suzana, Leach, Michael W., Pelker, Jeffrey W., Azoitei, Mihai L., Uozumi, Naonori, Cui, Junqing, Shen, Marina W.H., DeClercq, Charlene M., Miyashiro, Joy S., Carito, Brenda A., Thakker, Paresh, Simmons, David L., Leonard, John P., Shimizu, Takao, Clark, James D.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2005
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212947/
https://ncbi.nlm.nih.gov/pubmed/16172261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050665
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